Dr. LaTonia Taliaferro-Smith is the Director of Undergraduate Laboratories, Faculty Coordinator for Summer Programs, and an Associate Teaching Professor in Biology at Oxford College of Emory University. She received a B.S. in Biology (with Highest Honors) from Dillard University and a Ph.D. in Biochemistry and Molecular Biology from Howard University. Following graduate school, Dr. Taliaferro-Smith completed two postdoctoral fellowships before being appointed as a junior faculty member at the Emory University School of Medicine and as a member of the Winship Cancer Institute.
Her research focuses on the molecular mechanisms that regulate the metastatic behavior of triple-negative breast cancers (TNBCs), a particularly aggressive disease with disproportionately high incidences and poor survival outcomes, especially among African-American and Hispanic women. Since joining the Oxford College of Emory University faculty in 2015, Dr. Taliaferro-Smith has developed and taught a diverse range of courses, including BIO-340E (Independent Research and Discovery in Biology), which she designed to provide early undergraduate research experiences. She also teaches BIO-399RE (Independent Research) and BIO-397R (Supervised Reading), offering opportunities for advanced biological study and research projects.
Her innovative teaching extends to interdisciplinary courses such as the first-year Discovery Seminars, "The History of Cancer" and "Biomimicry and Bio-inspirations," which bridges biology, engineering, and architecture, and and co-taught "Race, Rights, and Recognitions in STEM," a unique side-car course examining sociocultural factors and intersectional identities in scientific research.
As Director of Undergraduate Laboratories, Dr. Taliaferro-Smith manages laboratory preparations for all courses taught in the Biology department and serves as an academic advisor to first- and second-year students. In her role as Faculty Coordinator for Summer Programs, she is working to develop pre-college summer academic programming at Oxford. She remains deeply passionate about teaching, training, and mentoring the next generation of science scholars.
Dr. Taliaferro-Smith's excellence in teaching and mentoring has been widely recognized. She is a 2024 NSF Inclusive STEM Teaching Project Community Facilitator and was nominated for the Presidential Awards for Excellence in Science, Mathematics, and Engineering Mentoring Program in 2023. Her numerous accolades include the 2022 Emory Williams Distinguished Undergraduate Teaching Award, the Gregory-Rackley Faculty Career Development Award, and the Robert Cotter Mizzell and Louise Felker Mizell Teaching Award. She was also honored with the Bloom Inaugural Black Women Excellence Award from Emory University, reflecting her outstanding contributions to both teaching and mentorship.
BS| Dillard University| 1999
Ph.D.| Howard University| 2004
Magazine publications/appearances:
SciOx Research Magazine. Annual publication (published August 2021-present, 4th edition published Spring 2024)). Oxford College of Emory University (https://scioxmagazine.com/)
Forbes Magazine, Science Engagement Shapes Lives and Changes Perceptions, by Marshall Sheppard, Senior Contributor, March 24, 2024 (https://www.forbes.com/sites/marshallshepherd/2024/03/24/science-engagement-shapes-lives-and-changes-perceptions-too/?sh=6e684a9a15ea)
Peer-reviewed journals
L Taliaferro-Smith, E Oberlick, T Liu, TZ McGlothen, TY Alcaide, R Tobin, et al. (2015) FAK activation is required for IGF1R mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cells. Oncotarget, 6(7); 4757-4772 (PMCID4467113)
E Sanabria-Figueroa, S Donnelly; K Foy; M Buss; RC Castellino; E Paplomata; L Taliaferro-Smith; P Kaumaya; R Nahta (2014) Insulin-like growth factor-1 receptor signaling increases the invasive potential of HER2-overexpressing breast cancer cells via Src-FAK and FoxM1. Molecular Pharmacology, 87(2):150-161. (PMID: 25391374)
Smith BN, Burton LJ, Henderson V, Randle DD, Morton DJ, Smith BA, Taliaferro-Smith L, et al. (2014) Snail Promotes Epithelial Mesenchymal Transition in Breast Cancer Cells in Part via Activation of Nuclear ERK2. PLoS One, 9(8): e104987. (PMID: 25122124)
PN Ganji, TE Long, W Park, JC Landry, L Taliaferro-Smith, AB Farris, R Diaz, BF El-Rayes (2014) Heat Shock Protein 90 Promotes Epithelial to Mesenchymal Transition, Invasion, and Migration in Colorectal Cancer. Molecular Pharmacology, 54(10):1147-1158. (PMID: 24861206).
PN Ganji, P Wungki, J Wen, H Mahaseth, J Landry, AB Farris, L Taliaferro-Smith, et al. (2013) Antiangiogenic effects of ganatespib in colorectal cancer mediated through inhibition of HIF1-aplha and STAT-3. Angiogenesis, 16(4):903-917. (PMID:23838996)
L Taliaferro-Smith, A Nagalingam, BB Knight, E Oberlick, NK Saxena, and D Sharma. (2013) Integral Role of PTP1B in Adiponectin-Mediated Inhibition of Oncogenic Actions of Leptin in Breast Carcinogenesis. Neoplasia, 15(1)23-38. (PMID: 23358729)
Tongrui Liu, Rami Yacoub, LaTonia Taliaferro-Smith, Shi-Yong Sun, Tisheeka R. Graham, Ryan Dolan, Mourad Tighiouart, et al. (2011) Combinatorial effects of lapatinib and rapamycin in triple-negative breast cancer cells. Molecular Cancer Therapeutics, 10(8)1460-1469. (PMID:21690228)
Nagaraju GP, Prasad GL, Taliaferro-Smith L, Aruna BV, Naik BR, Sekhar YN. Computational analysis of the structural basis of ligand binding to the crustacean retinoid X receptor. (2010) Comp Biochem Physiol Part D Genomics Proteomics 5(4):317-324. (PMID: 20937572)
Hill, KM., Kalifa, S., Das, J.R.,Bhatti, T., Gay, M., Williams, D., Taliferro-Smith, L. (name misspelled), and De Marzo, A.M. (2010) The Role of PI3-Kinase p110β in AKT Signally, Cell Survival, and Proliferation in Human Prostate Cancer Cells. Prostate, 70(7):755-764. (PMID:20058239)
Tisheeka R. Graham, Rami Yacoub, LaTonia Taliaferro-Smith, Adeboye O. Osunkoya, Valerie A. Odero-Marah, Tongrui Liu, et al. (2009) Reciprocal Regulation of ZEB1 and AR in Triple Negative 1 Breast Cancer Cells. Breast Cancer Research and Treatment, 123(1):139-147. (PMID: 19921427)
Taliaferro-Smith, L, Nagalingam, A., Zhong, D., Zhou, W., Saxena, N.K., and Sharma, D. (2009) LKB1 is required for adiponectin-mediated modulation of AMPK-S6K axis and inhibition of migration and invasion in breast cancer cells. Oncogene, 28(29):2621-2633. (PMID: 19483724)
Saxena, N. K., Taliaferro-Smith, L., Knight, B. B., Merlin, D., Anania, F. A., O'Regan, R. M., and Sharma, D. (2008) Bidirectional crosstalk between leptin and insulin-like growth factor-1 signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth factor receptor. Cancer Research, 68(23): 9712-9722. (PMID: 19047189)
C Bonilla, R K Panguluri, L Taliaferro-Smith, G Argyropoulos, G Chen, A A Adeyemo, et al. (2006) Agouti-related protein promoter variant associated with leanness and decreased risk for diabetes in West Africans. International Journal of Obesity, 30: 715-721. (PMID:16130030)
Friedberg, F. and Taliaferro, L. (2005) Calmodulin genes in zebrafish (revisited). Molecular Biology Reports, 32:55-60. (PMID: 15865211)
Leach FS, Koh M, Sharma K, McWilliams G, Talifero-Smith L (named misspelled), et al. (2002) Mismatch repair gene mutations in renal cell carcinoma. Cancer Biology and Therapy, 1(5):530-536. (PMID: 12496483)
Book chapter authored:
Colbert, L.S. and Taliaferro-Smith, L.T. (2013). Tumor Angiogenesis Regulators in Breast Cancer: Does Race Matter?” in Ruben R. Gonzalez-Perez and Bo R. Rueda (Ed.), Tumor Angiogenesis Regulators, (pp. 387-410). Boca Raton, FL: CRC Press.
Triple-negative breast cancer